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Contraindicated (one)pentobarbital will decrease the level or outcome of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is chargeable for the formation and elimination of cariprazine's active metabolites.pentobarbital will lessen the level or impact of fentanyl by influencing hepatic/intestinal enzyme

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